TSC22D1

TSC22D1
Identifiers
Aliases	TSC22D1, Ptg-2, TGFB1I4, TSC22, TSC22 domain family member 1
External IDs	OMIM: 607715; MGI: 109127; HomoloGene: 7573; GeneCards: TSC22D1; OMA:TSC22D1 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	44,577,147 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	76,745,205 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; Brodmann area 23; ; middle temporal gyrus; ; tibia; ; dorsal motor nucleus of vagus nerve; ; postcentral gyrus; ; beta cell; ; entorhinal cortex; ; mucosa of paranasal sinus; ; caput epididymis;
	Top expressed in
	iris; ; medullary collecting duct; ; renal corpuscle; ; vestibular sensory epithelium; ; epithelium of lens; ; Epithelium of choroid plexus; ; ciliary body; ; condyle; ; fossa; ; vas deferens;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; nucleus;
Biological process	regulation of transcription, DNA-templated; transcription by RNA polymerase II; transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	8848
	21807
	ENSG00000102804
	ENSMUSG00000022010
	Q15714
	P62500
	NM_001243797; NM_001243798; NM_001243799; NM_006022; NM_183422
	NM_001177751; NM_009366; NM_207652; NM_001310646; NM_001310647
	NP_001230726; NP_001230727; NP_001230728; NP_006013; NP_904358
	NP_001171222; NP_001297575; NP_001297576; NP_033392; NP_997535
	Wikidata
View/Edit Human	View/Edit Mouse

TSC22 domain family protein 1 is a protein that in humans is encoded by the TSC22D1 gene.

TSC22 encodes a transcription factor and belongs to the large family of early response genes.

TSC22D1 forms homodimers via its conserved leucine zipper domain and heterodimerizes with TSC22D4. TSC22D1 has transcriptional repressor activity.