TSPAN12

TSPAN12
Identifiers
Aliases	TSPAN12, EVR5, NET-2, NET2, TM4SF12, tetraspanin 12
External IDs	OMIM: 613138; MGI: 1889818; HomoloGene: 8212; GeneCards: TSPAN12; OMA:TSPAN12 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	120,858,402 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	21,852,514 bp
RNA expression pattern
	Top expressed in
	oocyte; ; kidney tubule; ; secondary oocyte; ; right adrenal gland; ; right ventricle; ; lower lobe of lung; ; jejunal mucosa; ; glomerulus; ; metanephric glomerulus; ; left adrenal gland;
	Top expressed in
	brown adipose tissue; ; parotid gland; ; submandibular gland; ; tunica adventitia of aorta; ; white adipose tissue; ; intercostal muscle; ; female external genitalia; ; liver; ; adrenal gland; ; mucosa of urinary bladder;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; Wnt-activated receptor activity;
Cellular component	membrane; plasma membrane; integral component of membrane; integral component of plasma membrane;
Biological process	angiogenesis; retina layer formation; regulation of angiogenesis; cell surface receptor signaling pathway; Wnt signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	23554
	269831
	ENSG00000106025
	ENSMUSG00000029669
	O95859
	Q8BKT6
	NM_012338
	NM_173007; NM_001363814
	NP_036470
	NP_766595; NP_001350743
	Wikidata
View/Edit Human	View/Edit Mouse

Tetraspanin-12 (Tspan-12) also known as tetraspan NET-2 (NET2) or transmembrane 4 superfamily member 12 (TM4SF12) is a tetraspanin protein that in humans is encoded by the TSPAN12 gene. Tetraspanin-12 is found in the membrane of a variety of cells. It has an unusually long C-terminal intracellular tail of approximately 60 amino acids.