TSPAN6

TSPAN6
Identifiers
AliasesTSPAN6, T245, TM4SF6, TSPAN-6, tetraspanin 6
External IDsOMIM: 300191; MGI: 1926264; HomoloGene: 20700; GeneCards: TSPAN6; OMA:TSPAN6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

7105

56496

Ensembl

ENSG00000000003

ENSMUSG00000067377

UniProt

O43657

O70401

RefSeq (mRNA)

NM_001278740
NM_001278741
NM_001278742
NM_001278743
NM_003270

NM_019656

RefSeq (protein)

NP_001265669
NP_001265670
NP_001265671
NP_001265672
NP_003261

n/a

Location (UCSC)Chr X: 100.63 – 100.64 MbChr X: 132.79 – 132.8 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Tetraspanin-6 is a protein that in humans is encoded by the TSPAN6 gene.

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The use of alternate polyadenylation sites has been found for this gene.