TTBK1

TTBK1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4BTJ, 4BTK, 4BTM, 4NFM, 4NFN
Identifiers
Aliases	TTBK1, BDTK, tau tubulin kinase 1
External IDs	MGI: 2147036; HomoloGene: 50342; GeneCards: TTBK1; OMA:TTBK1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	43,288,258 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	46,798,601 bp
RNA expression pattern
	Top expressed in
	lateral nuclear group of thalamus; ; prefrontal cortex; ; postcentral gyrus; ; right frontal lobe; ; right hemisphere of cerebellum; ; superior frontal gyrus; ; anterior cingulate cortex; ; entorhinal cortex; ; Brodmann area 9; ; Amygdala;
	Top expressed in
	superior frontal gyrus; ; primary visual cortex; ; seminiferous tubule; ; dentate gyrus of hippocampal formation granule cell; ; cerebellar cortex; ; Rostral migratory stream; ; primary motor cortex; ; cingulate gyrus; ; spermatid; ; subiculum;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; ATP binding; kinase activity; tau protein binding; tau-protein kinase activity;
Cellular component	cytoplasm; nucleus; nucleoplasm; cytosol; microtubule associated complex; soma; perinuclear region of cytoplasm;
Biological process	protein phosphorylation; peptidyl-serine phosphorylation; substantia nigra development; phosphorylation; regulation of cell shape; learning or memory; positive regulation of gene expression; negative regulation of gene expression; peptidyl-threonine phosphorylation; peptidyl-tyrosine phosphorylation; negative regulation of protein binding; positive regulation of protein polymerization; positive regulation of astrocyte activation; positive regulation of microglial cell activation; positive regulation of cyclin-dependent protein kinase activity; positive regulation of cysteine-type endopeptidase activity;
	Sources:Amigo / QuickGO
Orthologs
	84630
	106763
	ENSG00000146216
	ENSMUSG00000015599
	Q5TCY1
	Q6PCN3
	NM_032538
	NM_001162864; NM_175351
	NP_115927
	NP_001156336
	Wikidata
View/Edit Human	View/Edit Mouse

Tau tubulin kinase 1 is a protein that in humans is encoded by the TTBK1 gene.