TTC8

TTC8
Identifiers
Aliases	TTC8, BBS8, RP51, tetratricopeptide repeat domain 8
External IDs	OMIM: 608132; MGI: 1923510; HomoloGene: 14988; GeneCards: TTC8; OMA:TTC8 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	88,881,078 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	98,949,497 bp
RNA expression pattern
	Top expressed in
	left ovary; ; islet of Langerhans; ; right adrenal cortex; ; right uterine tube; ; pituitary gland; ; right ovary; ; anterior pituitary; ; left adrenal gland; ; left adrenal cortex; ; stromal cell of endometrium;
	Top expressed in
	neural layer of retina; ; olfactory epithelium; ; genital tubercle; ; median eminence; ; arcuate nucleus; ; pineal gland; ; tail of embryo; ; habenula; ; paraventricular nucleus of hypothalamus; ; dorsomedial hypothalamic nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; ciliary basal body; cytosol; centrosome; plasma membrane; cell projection; cilium; cytoskeleton; membrane; ciliary membrane; microtubule organizing center; BBSome; non-motile cilium; photoreceptor connecting cilium;
Biological process	protein transport; establishment of anatomical structure orientation; sensory processing; cell projection organization; cilium assembly; non-motile cilium assembly; axon guidance; sensory perception of smell; olfactory bulb development; negative regulation of GTPase activity; camera-type eye photoreceptor cell differentiation; renal tubule development; fat cell differentiation; regulation of stress fiber assembly; multicellular organism growth; regulation of protein localization; establishment of planar polarity; inner ear receptor cell stereocilium organization; multi-ciliated epithelial cell differentiation; protein localization to plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	123016
	76260
	ENSG00000165533
	ENSMUSG00000021013
	Q8TAM2
	Q8VD72
NM_001288781; NM_001288782; NM_001288783; NM_144596; NM_198309;
	NM_198310; NM_001366535; NM_001366536
	NM_029553; NM_198311; NM_001364378
NP_001275710; NP_001275711; NP_001275712; NP_653197; NP_938051;
	NP_938052; NP_001353464; NP_001353465; NP_001275710.1
	NP_083829; NP_938053; NP_001351307
	Wikidata
View/Edit Human	View/Edit Mouse

Tetratricopeptide repeat domain 8 (TTC8) also known as Bardet–Biedl syndrome 8 is a protein that in humans is encoded by the TTC8 gene.