MYOT

MYOT
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2KDG, 2KKQ
Identifiers
Aliases	MYOT, LGMD1, LGMD1A, MFM3, TTID, TTOD, myotilin
External IDs	OMIM: 604103; MGI: 1889800; HomoloGene: 4942; GeneCards: MYOT; OMA:MYOT - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	137,887,851 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	44,488,791 bp
RNA expression pattern
	Top expressed in
	muscle of thigh; ; gastrocnemius muscle; ; Skeletal muscle tissue of rectus abdominis; ; Skeletal muscle tissue of biceps brachii; ; vastus lateralis muscle; ; body of tongue; ; buccal mucosa cell; ; Achilles tendon; ; deltoid muscle; ; testicle;
	Top expressed in
	digastric muscle; ; temporal muscle; ; soleus muscle; ; triceps brachii muscle; ; sternocleidomastoid muscle; ; muscle of thigh; ; ankle; ; vastus lateralis muscle; ; intercostal muscle; ; thoracic diaphragm;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	actin binding; structural constituent of muscle; protein binding; alpha-actinin binding; axon guidance receptor activity;
Cellular component	cytoplasm; sarcolemma; plasma membrane; Z discdkac; cytoskeleton; membrane; actin cytoskeleton; axon; soma;
Biological process	muscle contraction; homophilic cell adhesion via plasma membrane adhesion molecules; axon guidance; synapse organization;
	Sources:Amigo / QuickGO
Orthologs
	9499
	58916
	ENSG00000120729
	ENSMUSG00000024471
	Q9UBF9
	Q9JIF9
	NM_006790; NM_001135940; NM_001300911
	NM_001033621
	NP_001129412; NP_001287840; NP_006781
	NP_001028793
	Wikidata
View/Edit Human	View/Edit Mouse

Myotilin is a protein that in humans is encoded by the MYOT gene. Myotilin (myofibrillar titin-like protein) also known as TTID (TiTin Immunoglobulin Domain) is a muscle protein that is found within the Z-disc of sarcomeres.