TTLL1

TTLL1
Identifiers
Aliases	TTLL1, C22orf7, HS323M22B, tubulin tyrosine ligase like 1, TTL family tubulin polyglutamylase complex subunit L1, TPGS3
External IDs	OMIM: 608955; MGI: 2443047; HomoloGene: 8174; GeneCards: TTLL1; OMA:TTLL1 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	43,089,419 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	83,395,094 bp
RNA expression pattern
	Top expressed in
	gonad; ; ganglionic eminence; ; bronchial epithelial cell; ; ventricular zone; ; testicle; ; mucosa of paranasal sinus; ; prefrontal cortex; ; frontal pole; ; right uterine tube; ; oocyte;
	Top expressed in
	myocardium of ventricle; ; interventricular septum; ; right ventricle; ; Rostral migratory stream; ; cardiac muscles; ; facial motor nucleus; ; anterior horn of spinal cord; ; dorsomedial hypothalamic nucleus; ; median eminence; ; paraventricular nucleus of hypothalamus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; ligase activity; ATP binding; tubulin-glutamic acid ligase activity;
Cellular component	cytoplasm; microtubule; cytoskeleton; extracellular region;
Biological process	epithelial cilium movement involved in extracellular fluid movement; protein polyglutamylation; axoneme assembly; sperm axoneme assembly;
	Sources:Amigo / QuickGO
Orthologs
	25809
	319953
	ENSG00000100271
	ENSMUSG00000022442
	O95922
	Q91V51
	NM_001008572; NM_012263
	NM_178869; NM_001357953
	NP_036395
	NP_849200; NP_001344882
	Wikidata
View/Edit Human	View/Edit Mouse

Probable tubulin polyglutamylase TTLL1 is an enzyme that in humans is encoded by the TTLL1 gene.