Tubulin beta-4B chain

TUBB4B
Identifiers
Aliases	TUBB4B, Beta2, TUBB2, TUBB2C, tubulin beta 4B class IVb, LCAEOD
External IDs	OMIM: 602660; MGI: 1915472; HomoloGene: 68504; GeneCards: TUBB4B; OMA:TUBB4B - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	137,243,707 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	25,114,714 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; bronchial epithelial cell; ; right uterine tube; ; spinal ganglia; ; olfactory zone of nasal mucosa; ; pars compacta; ; mucosa of ileum; ; orbitofrontal cortex; ; Brodmann area 46;
	Top expressed in
	spermatid; ; testicle; ; spermatocyte; ; primary oocyte; ; secondary oocyte; ; Hypothalamus; ; esophagus; ; bone marrow; ; lens; ; epiblast;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; unfolded protein binding; GTP binding; structural constituent of cytoskeleton; GTPase activity; double-stranded RNA binding; MHC class I protein binding;
Cellular component	cytoplasm; extracellular vesicle; cytosol; myelin sheath; microtubule; cytoskeleton; extracellular exosome; nucleus; extracellular matrix; extracellular region; microtubule cytoskeleton; azurophil granule lumen;
Biological process	G2/M transition of mitotic cell cycle; microtubule-based process; natural killer cell mediated cytotoxicity; cytoskeleton organization; neutrophil degranulation; ciliary basal body-plasma membrane docking; regulation of G2/M transition of mitotic cell cycle; microtubule cytoskeleton organization; mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	10383
	227613
	ENSG00000188229
	ENSMUSG00000036752
	P68371
	P68372
	NM_006088
	NM_146116
	NP_006079
	NP_666228
	Wikidata
View/Edit Human	View/Edit Mouse

Tubulin beta-4B chain formerly known as tubulin beta-2C chain is a protein that in humans is encoded by the TUBB4B gene. It is thought that this protein could determine which hand is dominant in humans due to variations of the TUBB4B gene, which cause the protein to form microtubules that form cilia which direct fluids asymmetrically during development.