ZCCHC6

TUT7
Identifiers
Aliases	TUT7, PAPD6, zinc finger CCHC-type containing 6, TENT3B, ZCCHC6, terminal uridylyl transferase 7
External IDs	OMIM: 613467; MGI: 2387179; HomoloGene: 51941; GeneCards: TUT7; OMA:TUT7 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	86,354,454 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	59,970,961 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; blood; ; buccal mucosa cell; ; periodontal fiber; ; Achilles tendon; ; skin of thigh; ; monocyte; ; epithelium of nasopharynx; ; bone marrow cells; ; oral cavity;
	Top expressed in
	basilar part of occipital bone; ; granulocyte; ; tibiofemoral joint; ; bone marrow; ; genital tubercle; ; jejunum; ; fetal liver hematopoietic progenitor cell; ; renal corpuscle; ; ileum; ; blood;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotidyltransferase activity; zinc ion binding; metal ion binding; nucleic acid binding; RNA binding; RNA uridylyltransferase activity; protein binding; miRNA binding; uridylyltransferase activity;
Cellular component	cytoplasm; nucleoplasm; cytosol;
Biological process	histone mRNA catabolic process; RNA 3'-end processing; nuclear-transcribed mRNA poly(A) tail shortening; oocyte maturation; negative regulation of transposition, RNA-mediated; miRNA metabolic process; pre-miRNA processing; RNA 3' uridylation; polyuridylation-dependent mRNA catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	79670
	214290
	ENSG00000083223
	ENSMUSG00000035248
	Q5VYS8
	Q5BLK4
	NM_001185059; NM_001185074; NM_024617; NM_001330718
	NM_153538; NM_001373962; NM_001373963; NM_001373964
	NP_001171988; NP_001172003; NP_001317647; NP_078893
	NP_705766; NP_001360891; NP_001360892; NP_001360893
	Wikidata
View/Edit Human	View/Edit Mouse

Terminal uridylyltransferase 7 (TUT7), also known as "zinc finger, CCHC domain containing 6", is an enzyme that in humans is encoded by the ZCCHC6 gene located on chromosome 9. The ZCCHC6 protein mediates the terminal uridylation of RNA transcripts with short poly-A tails and is involved in mRNA and microRNA degradation