NME8

NME8
Identifiers
Aliases	NME8, CILD6, NM23-H8, SPTRX2, TXNDC3, sptrx-2, HEL-S-99, NME/NM23 family member 8, DNAI8
External IDs	OMIM: 607421; MGI: 1920662; HomoloGene: 9593; GeneCards: NME8; OMA:NME8 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	37,900,397 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	19,881,964 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; testicle; ; gonad; ; monocyte; ; right testis; ; left testis; ; sperm; ; blood; ; bone marrow; ; bone marrow cells;
	Top expressed in
	spermatid; ; seminiferous tubule; ; spermatocyte; ; embryo; ; Gonadal ridge; ; bone marrow; ; fossa; ; ventricle of the heart; ; islet of Langerhans; ; lens;
	More reference expression data
	n/a
Gene ontology
Molecular function	microtubule binding; nucleoside diphosphate kinase activity;
Cellular component	cytoplasm; sperm principal piece; sperm cytoplasmic droplet; outer dynein arm;
Biological process	multicellular organism development; flagellated sperm motility; cellular response to reactive oxygen species; cell differentiation; nucleoside diphosphate phosphorylation; spermatogenesis; cell redox homeostasis; cilium assembly;
	Sources:Amigo / QuickGO
Orthologs
	51314
	73412
	ENSG00000086288
	ENSMUSG00000041138
	Q8N427
	Q715T0
	NM_016616
	NM_001167909; NM_181591
	NP_057700
	NP_001161381; NP_853622
	Wikidata
View/Edit Human	View/Edit Mouse

Thioredoxin domain-containing protein 3 (TXNDC3), also known as spermatid-specific thioredoxin-2 (Sptrx-2), is a protein that in humans is encoded by the NME8 gene (also known as the TXNDC3 gene) on chromosome 7.