TYRP1

TYRP1
Identifiers
Aliases	TYRP1, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN, tyrosinase related protein 1
External IDs	OMIM: 115501; MGI: 98881; HomoloGene: 464; GeneCards: TYRP1; OMA:TYRP1 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	12,710,285 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	80,769,956 bp
RNA expression pattern
	Top expressed in
	retinal pigment epithelium; ; skin of thigh; ; vulva; ; human penis; ; skin of arm; ; Epithelium of choroid plexus; ; skin of hip; ; nipple; ; right ventricle; ; myocardium of left ventricle;
	Top expressed in
	iris; ; ciliary body; ; hair follicle; ; retinal pigment epithelium; ; lumbar spinal ganglion; ; epithelium of lens; ; choroid; ; habenula; ; cornea; ; conjunctival fornix;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; metal ion binding; monooxygenase activity; protein binding; protein heterodimerization activity; oxidoreductase activity; tyrosinase activity;
Cellular component	integral component of membrane; clathrin-coated endocytic vesicle membrane; membrane; melanosome; endosome membrane; melanosome membrane; cytoplasm; intracellular vesicle;
Biological process	melanin metabolic process; melanosome organization; positive regulation of melanin biosynthetic process; pigmentation; metabolism; melanocyte differentiation; acetoacetic acid metabolic process; melanin biosynthetic process; response to thyroid hormone;
	Sources:Amigo / QuickGO
Orthologs
	7306
	22178
	ENSG00000107165
	ENSMUSG00000005994
	P17643
	P07147
	NM_000550
	NM_001282014; NM_001282015; NM_031202
	NP_000541
	NP_001268943; NP_001268944; NP_112479
	Wikidata
View/Edit Human	View/Edit Mouse

Tyrosinase-related protein 1, also known as TYRP1, is an intermembrane enzyme which in humans is encoded by the TYRP1 gene.