Taça Regional de São Tomé
| Founded | 1981 (unilateral) 2004 (entirety) |
|---|---|
| Region | São Tomé Island, São Tomé and Príncipe |
| Number of teams | 32 |
| Current champions | UDRA (5th time) |
| Most successful club(s) | Vitória FC (Riboque) and UDRA (5 titles) |
Taça Regional de São Tomé, literally the São Tomé Regional Cup is the regional knockout tournament of the island of São Tomé, it was unilaterally created in 1981 and was entirely created in 2001. The winner competes with the Príncipe Cup winner in the São Tomé and Príncipe Cup.