Tennessee State Route 381
| State of Franklin Road | ||||
| Route information | ||||
| Maintained by TDOT | ||||
| Length | 7.7 mi (12.4 km) | |||
| Existed | July 1, 1983–present | |||
| Major junctions | ||||
| South end | US 321 / SR 67 in Johnson City | |||
| North end | US 11E / US 19W in North Johnson City | |||
| Location | ||||
| Country | United States | |||
| State | Tennessee | |||
| Counties | Washington | |||
| Highway system | ||||
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State Route 381 (SR 381) is a state highway in Johnson City, Washington County, Tennessee. It serves as a bypass of Downtown on the north, west and south sides of the city. The route is also a retail corridor, lined with stores, restaurants and hotels.