Tetrahydrocannabivarin

Tetrahydrocannabivarin
Clinical data
Routes of
administration
Oral, smoked, inhaled
ATC code
  • None
Legal status
Legal status
  • US: Unscheduled
  • Also legal in UK, Canada and Netherlands
Identifiers
  • 6,6,9-Trimethyl-3-propyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC19H26O2
Molar mass286.415 g·mol−1
3D model (JSmol)
  • CCCC1=CC2=C(C3C=C(CCC3C(O2)(C)C)C)C(=C1)O
  • InChI=1S/C19H26O2/c1-5-6-13-10-16(20)18-14-9-12(2)7-8-15(14)19(3,4)21-17(18)11-13/h9-11,14-15,20H,5-8H2,1-4H3/t14-,15-/m1/s1 Y
  • Key:ZROLHBHDLIHEMS-HUUCEWRRSA-N Y
 NY (what is this?)  (verify)

Tetrahydrocannabivarin (THCV, THV, O-4394, GWP42004) is a homologue of tetrahydrocannabinol (THC) having a propyl (3-carbon) side chain instead of pentyl (5-carbon), making it non-psychoactive in lower doses. It has been shown to exhibit neuroprotective activity, appetite suppression, glycemic control and reduced side effects compared to THC, making it a potential treatment for management of obesity and diabetes. THCV was studied by Roger Adams as early as 1942.