Tetrahydrogestrinone

Tetrahydrogestrinone
Clinical data
Other names	THG; The Clear; 17α-Ethyl-18-methyl-δ9,11-19-nortestosterone; 17α-Ethyl-18-methylestra-4,9,11-trien-17β-ol-3-one
Routes of; administration	By mouth, intramuscular injection
Drug class	Androgen; Anabolic steroid; Progestogen
Legal status
Legal status	US: Schedule III;
Identifiers
	IUPAC name (8S,13S,14S,17S)-13,17-diethyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one;
CAS Number	618903-56-3 ;
PubChem CID	6857686;
DrugBank	DB06870 ;
ChemSpider	5257020 ;
UNII	643MR6L9LB;
CompTox Dashboard (EPA)	DTXSID60210901 ;
Chemical and physical data
Formula	C21H28O2
Molar mass	312.453 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C1C=C2C(CC1)=C3C=C[C@@]4(CC)[C@@]([C@]3([H])CC2)([H])CC[C@]4(CC)O;
	InChI InChI=1S/C21H28O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h9,11,13,18-19,23H,3-8,10,12H2,1-2H3/t18-,19+,20+,21+/m1/s1 ; Key:OXHNQTSIKGHVBH-ANULTFPQSA-N ;
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Tetrahydrogestrinone (THG), known by the nickname The Clear, is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never marketed for medical use. It was developed by Patrick Arnold and was used by a number of high-profile athletes such as Barry Bonds and Dwain Chambers.

Clinical data

Other names	THG; The Clear; 17α-Ethyl-18-methyl-δ^9,11-19-nortestosterone; 17α-Ethyl-18-methylestra-4,9,11-trien-17β-ol-3-one
Routes of administration	By mouth, intramuscular injection
Drug class	Androgen; Anabolic steroid; Progestogen
Legal status
Legal status	US: Schedule III
Identifiers
IUPAC name (8S,13S,14S,17S)-13,17-diethyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
CAS Number	618903-56-3^N
PubChem CID	6857686
DrugBank	DB06870^Y
ChemSpider	5257020^Y
UNII	643MR6L9LB
CompTox Dashboard (EPA)	DTXSID60210901
Chemical and physical data
Formula	C₂₁H₂₈O₂
Molar mass	312.453 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C1C=C2C(CC1)=C3C=C[C@@]4(CC)[C@@]([C@]3([H])CC2)([H])CC[C@]4(CC)O
InChI InChI=1S/C21H28O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h9,11,13,18-19,23H,3-8,10,12H2,1-2H3/t18-,19+,20+,21+/m1/s1^Y Key:OXHNQTSIKGHVBH-ANULTFPQSA-N^Y
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