Rhodanese
| Rhodanese-like domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Rhodanese | ||||||||
| Pfam | PF00581 | ||||||||
| InterPro | IPR001763 | ||||||||
| PROSITE | PDOC00322 | ||||||||
| SCOP2 | 2ora / SCOPe / SUPFAM | ||||||||
| OPM superfamily | 413 | ||||||||
| OPM protein | 2mpn | ||||||||
| CDD | cd00158 | ||||||||
| Membranome | 571 | ||||||||
| |||||||||
| thiosulfate sulfurtransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.8.1.1 | ||||||||
| CAS no. | 9026-04-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Rhodanese is a mitochondrial enzyme that detoxifies cyanide (CN−) by converting it to thiocyanate (SCN−, also known as "rhodanate"). In enzymatology, the common name is listed as thiosulfate sulfurtransferase (EC 2.8.1.1). The diagram on the right shows the crystallographically-determined structure of rhodanese.
It catalyzes the following reaction:
- thiosulfate + cyanide sulfite + thiocyanate
