Tla-o-qui-aht First Nations
| Traditional territory of the Tla-o-qui-aht First Nations | |
| People | Nuu-chah-nulth | 
|---|---|
| Headquarters | Meares Island | 
| Province | British Columbia | 
| Land | |
| Main reserve | Opitsat 1 | 
| Other reserve(s) | List 
 | 
| Land area | 3.878 km2 | 
| Population (2025) | |
| On reserve | 399 | 
| On other land | 57 | 
| Off reserve | 786 | 
| Total population | 1242 | 
| Government | |
| Chief | Elmer Frank | 
| Tribal Council | |
| Nuu-chah-nulth Tribal Council | |
| Website | |
| www | |
The Tla-o-qui-aht First Nations (Nuu-chah-nulth: ƛaʔuukʷiʔatḥ) are a Nuu-chah-nulth First Nation (band government) in Canada. They live on ten reserves along the Pacific Rim National Park Reserve on Vancouver Island, British Columbia. The band is part of the Nuu-chah-nulth Tribal Council. There were 618 people living in the Tla-o-qui-aht reserves in 1995. Their primary economic activities are fishing and tourism.