Topical steroid withdrawal

Topical steroid withdrawal
Other namesTopical steroid addiction, steroid dermatitis, red burning skin syndrome, red skin syndrome, iatrogenic exfoliative dermatitis (idiopathic erythroderma)
Red burning skin syndrome from topical steroids. Face pattern with nose sign and spared palms (soles also spared)
SpecialtyDermatology
SymptomsRed skin, burning sensation, desquamation, itchiness
CausesStopping topical steroids after frequent long-term use
PreventionUsing steroid creams for less than two weeks
FrequencyNot known

Topical steroid withdrawal, also known as red burning skin and steroid dermatitis, has been reported in people who apply topical steroids for 2 weeks or longer and then discontinue use. Symptoms affect the skin and include redness, a burning sensation, and itchiness, which may then be followed by peeling.

This condition generally requires the daily application of a topical steroid for more than 2 weeks but sometimes can occur with even less steroid use. It appears to be a specific adverse effect of topical corticosteroid use. People with atopic dermatitis are most at risk.

Treatment involves discontinuing the use of topical steroids, either gradually or suddenly. Counselling and cold compresses may also help. Thousands of people congregate in online communities to support one another throughout the healing process, and cases have been reported in both adults and children. It was first described in 1979.