Torsades de pointes

Torsades de pointes
Other namesTorsade(s)
12-lead ECG of torsades de pointes (TdP) in a 56-year-old white female with low blood potassium (2.4 mmol/L) and low blood magnesium (1.6 mg/dL)
SpecialtyCardiology
ComplicationsCardiac arrest
CausesHereditary, certain drugs, electrolyte disorders which cause increased QT interval
Risk factorsMedications, hypokalemia, hypomagnesemia, hypocalcemia, bradycardia, heart failure, left ventricular hypertrophy, hypothermia, subarachnoid hemorrhage, hypothyroidism
Deaths~5% of 300,000 sudden cardiac deaths in the US

Torsades de pointes, torsade de pointes or torsades des pointes (TdP; also called torsades) (/tɔːrˌsɑːd də ˈpwæ̃t/, French: [tɔʁsad pwɛ̃t̪], translated as "twisting of peaks") is a specific type of abnormal heart rhythm that can lead to sudden cardiac death. It is a polymorphic ventricular tachycardia that exhibits distinct characteristics on the electrocardiogram (ECG). It was described by French physician François Dessertenne in 1966. Prolongation of the QT interval can increase a person's risk of developing this abnormal heart rhythm, occurring in between 1% and 10% of patients who receive QT-prolonging antiarrhythmic drugs.