Transfusion-related acute lung injury

Transfusion-related acute lung injury
Other namesTRALI
Micrograph of diffuse alveolar damage, the histologic correlate of TRALI; H&E stain
SpecialtyPulmonology

Transfusion-related acute lung injury (TRALI) is the serious complication of transfusion of blood products that is characterized by the rapid onset of excess fluid in the lungs. It can cause dangerous drops in the supply of oxygen to body tissues. Although changes in transfusion practices have reduced the incidence of TRALI, it was the leading cause of transfusion-related deaths in the United States from fiscal year 2008 through fiscal year 2012.

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