Triacylglycerol lipase
| Triacylglycerol lipase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.1.3 | ||||||||
| CAS no. | 9001-62-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
| Lipase (class 3) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Structure of Triacyl-glycerol acylhydrolase. | |||||||||
| Identifiers | |||||||||
| Symbol | Lipase_3 | ||||||||
| Pfam | PF01764 | ||||||||
| InterPro | IPR002921 | ||||||||
| PROSITE | PDOC00110 | ||||||||
| SCOP2 | 3tgl / SCOPe / SUPFAM | ||||||||
| OPM superfamily | 127 | ||||||||
| OPM protein | 3tgl | ||||||||
| CDD | cd00519 | ||||||||
| |||||||||
The enzyme triacylglycerol lipase (also triglyceride lipase, EC 3.1.1.3;systematic name triacylglycerol acylhydrolase) catalyses the hydrolysis of ester linkages of triglycerides:
- triacylglycerol + H2O ⇌ diacylglycerol + a carboxylate
These lipases are widely distributed in animals, plants and prokaryotes. This family was also called class 3 lipases as they are only distantly related to other lipase families.