Tudor domain
| TUDOR domain | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Structure of a TUDOR domain. | |||||||||||
| Identifiers | |||||||||||
| Symbol | TUDOR | ||||||||||
| Pfam | PF00567 | ||||||||||
| Pfam clan | CL0049 | ||||||||||
| InterPro | IPR008191 | ||||||||||
| SMART | TUDOR | ||||||||||
| PROSITE | PDOC50304 | ||||||||||
| SCOP2 | 3fdr / SCOPe / SUPFAM | ||||||||||
| CDD | cd04508 | ||||||||||
| |||||||||||
In molecular biology, a Tudor domain is a conserved protein structural domain originally identified in the Tudor protein encoded in Drosophila. The Tudor gene was found in a Drosophila screen for maternal factors that regulate embryonic development or fertility. Mutations here are lethal for offspring, inspiring the name Tudor, as a reference to the Tudor King Henry VIII and the several miscarriages experienced by his wives.