Hydrocortisone acetate

Hydrocortisone acetate
Clinical data
Other names	Cortisol 21-acetate
Drug class	Corticosteroid; Glucocorticoid
Identifiers
	IUPAC name [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate;
CAS Number	50-03-3 ;
PubChem CID	5744;
DrugBank	DB14539;
ChemSpider	5542;
UNII	3X7931PO74;
KEGG	D00165;
ChEBI	CHEBI:17609;
ChEMBL	ChEMBL1091;
CompTox Dashboard (EPA)	DTXSID20962156 DTXSID0048686, DTXSID20962156 ;
ECHA InfoCard	100.000.005
Chemical and physical data
Formula	C23H32O6
Molar mass	404.503 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)O;
	InChI InChI=1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1; Key:ALEXXDVDDISNDU-JZYPGELDSA-N;

Hydrocortisone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.

The acetate group helps to protect the hydrocortisone molecule from being broken down by enzymes in the body (prolongs the duration of action of hydrocortisone) and allows it to be absorbed more easily.