U.S. Route 150
| US 150 highlighted in red | |
| Route information | |
| Auxiliary route of US 50 | |
| Length | 571 mi (919 km) | 
| Existed | 1926–present | 
| Major junctions | |
| West end | US 6 in Moline, IL | 
| I-55 in Bloomington, IL I-57 in Champaign, IL I-74 in Danville, IL I-70 in Terre Haute, IN I-69 in Washington, IN I-64 / SR 62 in New Albany, IN I-264 in Louisville, KY I-65 in Louisville, KY I-264 near Wellington, KY I-265 in Fern Creek (Louisville), KY | |
| East end | US 25 / KY 1249 in Mount Vernon, KY | 
| Location | |
| Country | United States | 
| States | Illinois, Indiana, Kentucky | 
| Highway system | |
U.S. Route 150 (US 150) is a 571-mile (919 km) long northwest–southeast United States highway, signed as east–west. It runs from U.S. Route 6 outside of Moline, Illinois, to U.S. Route 25 in Mount Vernon, Kentucky.