U.S. Route 240
| Washington National Pike Wisconsin Avenue | |||||||
US 240 highlighted in red, US 240 Alt. in blue, and US 240 Truck in pink | |||||||
| Route information | |||||||
| Auxiliary route of US 40 | |||||||
| Existed | 1926–1972 | ||||||
| Major junctions | |||||||
| South end | US 50 in Washington, D.C. | ||||||
| I-270 / MD 355 near Bethesda, MD I-70 in Frederick, MD | |||||||
| North end | US 40 in Frederick, MD | ||||||
| Location | |||||||
| Country | United States | ||||||
| States | District of Columbia, Maryland | ||||||
| Counties | DC: Washington MD: Montgomery, Frederick | ||||||
| Highway system | |||||||
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U.S. Route 240 is a defunct designation for a short, but once very important, segment of highway between Frederick, Maryland, and Washington, D.C. It is now commonly known as Wisconsin Avenue, Maryland Route 355 (MD 355), and Interstate 270 (I-270).