UACA

UACA
Identifiers
Aliases	UACA, NUCLING, uveal autoantigen with coiled-coil domains and ankyrin repeats
External IDs	OMIM: 612516; MGI: 1919815; HomoloGene: 74297; GeneCards: UACA; OMA:UACA - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	70,763,558 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	60,787,652 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; pancreatic ductal cell; ; sural nerve; ; cardia; ; renal medulla; ; ventral tegmental area; ; pylorus; ; nipple; ; trigeminal ganglion; ; subthalamic nucleus;
	Top expressed in
	otolith organ; ; ankle; ; utricle; ; muscle of thigh; ; tibialis anterior muscle; ; lumbar spinal ganglion; ; esophagus; ; medial head of gastrocnemius muscle; ; skeletal muscle tissue; ; knee joint;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; molecular function;
Cellular component	extracellular region; extracellular exosome; cytoskeleton; nucleus; cytoplasm; cytosol;
Biological process	apoptotic signaling pathway; regulation of NIK/NF-kappaB signaling; biological process;
	Sources:Amigo / QuickGO
Orthologs
	55075
	72565
	ENSG00000137831
	ENSMUSG00000034485
	Q9BZF9
	Q8CGB3
	NM_001008224; NM_018003
	NM_028283; NM_001357407; NM_001357408
	NP_001008225; NP_060473
	NP_082559; NP_001344336; NP_001344337
	Wikidata
View/Edit Human	View/Edit Mouse

Uveal autoantigen with coiled-coil domains and ankyrin repeats is a protein that in humans is encoded by the UACA gene. Diseases associated with UACA include Graves' Disease. Among its related pathways are signaling by Rho GTPases and Intrinsic Pathway for Apoptosis. An important paralog of this gene is ANKRD24.