UBA5

UBA5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3GUC, 3H8V, 5HKH
Identifiers
Aliases	UBA5, THIFP1, UBE1DC1, ubiquitin like modifier activating enzyme 5, SCAR24, EIEE44, DEE44
External IDs	OMIM: 610552; MGI: 1913913; HomoloGene: 11738; GeneCards: UBA5; OMA:UBA5 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	132,679,794 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	103,940,333 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; right adrenal gland; ; right adrenal cortex; ; left adrenal gland; ; left adrenal cortex; ; parotid gland; ; anterior pituitary; ; Achilles tendon; ; minor salivary glands; ; secondary oocyte;
	Top expressed in
	lacrimal gland; ; Ileal epithelium; ; parotid gland; ; seminal vesicula; ; fossa; ; islet of Langerhans; ; supraoptic nucleus; ; facial motor nucleus; ; substantia nigra; ; median eminence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein binding; ubiquitin-like modifier activating enzyme activity; ATP binding; metal ion binding; UFM1 activating enzyme activity;
Cellular component	cytoplasm; intracellular membrane-bounded organelle; nucleus; cytosol; Golgi apparatus;
Biological process	regulation of intracellular estrogen receptor signaling pathway; protein K69-linked ufmylation; response to endoplasmic reticulum stress; protein ufmylation; neuromuscular process; protein modification by small protein conjugation;
	Sources:Amigo / QuickGO
Orthologs
	79876
	66663
	ENSG00000081307
	ENSMUSG00000032557
	Q9GZZ9
	Q8VE47
	NM_024818; NM_198329; NM_001320210; NM_001321238; NM_001321239
	NM_025692
	NP_001307139; NP_001308167; NP_001308168; NP_079094; NP_938143
	NP_079968
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin-like modifier-activating enzyme 5 is a protein that in humans is encoded by the UBA5 gene.

This gene encodes a member of the E1-like activating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.