UBE2D3

UBE2D3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1X23, 2FUH, 3L1Z, 3RPG, 3UGB, 4BVU, 4R8P, 4S3O, 5IFR
Identifiers
Aliases	UBE2D3, E2(17)KB3, UBC4/5, UBCH5C, ubiquitin conjugating enzyme E2 D3
External IDs	OMIM: 602963; MGI: 1913355; HomoloGene: 123914; GeneCards: UBE2D3; OMA:UBE2D3 - orthologs
EC number	2.3.2.24
Gene location (Human)
Chr.	Chromosome 4 (human)
End	102,868,896 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	135,468,198 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; sperm; ; Achilles tendon; ; monocyte; ; buccal mucosa cell; ; blood; ; cartilage tissue; ; islet of Langerhans; ; appendix; ; right lung;
	Top expressed in
	genital tubercle; ; seminiferous tubule; ; tail of embryo; ; zygote; ; somite; ; secondary oocyte; ; dermis; ; molar; ; skin of external ear; ; abdominal wall;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein binding; ATP binding; ubiquitin conjugating enzyme activity; ubiquitin-protein transferase activity;
Cellular component	cytosol; endosome; membrane; plasma membrane; nucleoplasm; endosome membrane; extracellular exosome;
Biological process	positive regulation of protein targeting to mitochondrion; protein polyubiquitination; negative regulation of transcription by RNA polymerase II; protein monoubiquitination; BMP signaling pathway; cellular response to DNA damage stimulus; protein K11-linked ubiquitination; TRIF-dependent toll-like receptor signaling pathway; protein K48-linked ubiquitination; regulation of transcription from RNA polymerase II promoter in response to hypoxia; DNA repair; protein autoubiquitination; apoptotic process; protein ubiquitination; ubiquitin-dependent protein catabolic process; proteasome-mediated ubiquitin-dependent protein catabolic process; MyD88-independent toll-like receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	7323
	66105
	ENSG00000109332
	ENSMUSG00000078578
	P61077
	P61079
NM_001300795; NM_003340; NM_181886; NM_181887; NM_181888;
	NM_181889; NM_181890; NM_181891; NM_181892; NM_181893
	NM_025356
NP_001287724; NP_003331; NP_871615; NP_871616; NP_871617;
	NP_871618; NP_871619; NP_871620; NP_871621; NP_871622
NP_079632; NP_001343523; NP_001343524; NP_001343525; NP_001343526;
	NP_001343527
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin-conjugating enzyme E2 D3 is a protein that in humans is encoded by the UBE2D3 gene.