UBE2O

UBE2O
Identifiers
Aliases	UBE2O, E2-230K, ubiquitin conjugating enzyme E2 O
External IDs	OMIM: 617649; MGI: 2444266; HomoloGene: 11113; GeneCards: UBE2O; OMA:UBE2O - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	76,453,152 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	116,472,273 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; right frontal lobe; ; apex of heart; ; prefrontal cortex; ; gastrocnemius muscle; ; Brodmann area 9; ; ganglionic eminence; ; stromal cell of endometrium; ; islet of Langerhans; ; right lobe of thyroid gland;
	Top expressed in
	blood; ; tibiofemoral joint; ; primary visual cortex; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; perirhinal cortex; ; entorhinal cortex; ; fetal liver hematopoietic progenitor cell; ; CA3 field; ; central gray substance of midbrain;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein binding; ATP binding; ubiquitin conjugating enzyme activity; ubiquitin protein ligase binding; ubiquitin protein ligase activity; ubiquitin-protein transferase activity; RNA binding;
Cellular component	cytoplasm; nucleus; cytosol; nuclear body;
Biological process	positive regulation of BMP signaling pathway; protein K63-linked ubiquitination; retrograde transport, endosome to Golgi; protein monoubiquitination; protein ubiquitination; transport;
	Sources:Amigo / QuickGO
Orthologs
	63893
	217342
	ENSG00000175931
	ENSMUSG00000020802
	Q9C0C9
	Q6ZPJ3
	NM_022066
	NM_173755
	NP_071349
	NP_776116
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin-conjugating enzyme E2 O is a protein that in humans is encoded by the UBE2O gene.

UBE2O functions during terminal erythroid differentiation to eliminate generic cellular components in parallel with abundant synthesis of hemoglobin.