UBE2V2

UBE2V2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1J74, 1J7D, 1ZGU, 3VON, 4NR3, 4NRG, 4NRI, 4ONL, 4ONM, 4ONN, 4ORH, 5AIT
Identifiers
Aliases	UBE2V2, DDVIT1, DDVit-1, EDAF-1, EDPF-1, EDPF1, MMS2, UEV-2, UEV2, ubiquitin conjugating enzyme E2 V2
External IDs	OMIM: 603001; MGI: 1917870; HomoloGene: 55739; GeneCards: UBE2V2; OMA:UBE2V2 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	48,064,708 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	15,413,637 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; prefrontal cortex; ; Pons; ; Brodmann area 9; ; islet of Langerhans; ; Achilles tendon; ; cartilage tissue; ; Skeletal muscle tissue of rectus abdominis; ; oral cavity;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; embryo; ; embryo; ; ventricular zone; ; morula; ; blastocyst; ; primary visual cortex; ; superior frontal gyrus; ; yolk sac; ; muscle of thigh;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ubiquitin protein ligase activity; protein binding; ubiquitin conjugating enzyme activity; ubiquitin protein ligase binding;
Cellular component	cytoplasm; UBC13-MMS2 complex; extracellular exosome; nucleus; nucleoplasm;
Biological process	negative regulation of neuron apoptotic process; postreplication repair; protein K63-linked ubiquitination; regulation of DNA repair; DNA double-strand break processing; positive regulation of DNA repair; protein polyubiquitination; global genome nucleotide-excision repair; protein ubiquitination; error-free postreplication DNA repair; positive regulation of neuron projection development; cell population proliferation; double-strand break repair via nonhomologous end joining; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of synapse assembly;
	Sources:Amigo / QuickGO
Orthologs
	7336
	70620
	ENSG00000169139
	ENSMUSG00000022674
	Q15819
	Q9D2M8
	NM_003350
	NM_001159351; NM_023585
	NP_003341
	NP_001152823; NP_076074
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin-conjugating enzyme E2 variant 2 is a protein that in humans is encoded by the UBE2V2 gene. Ubiquitin-conjugating enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family.