UBIAD1

UBIAD1
Identifiers
Aliases	UBIAD1, SCCD, TERE1, UbiA prenyltransferase domain containing 1
External IDs	OMIM: 611632; MGI: 1918957; HomoloGene: 8336; GeneCards: UBIAD1; OMA:UBIAD1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	11,296,049 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	148,529,228 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; muscle of thigh; ; gonad; ; secondary oocyte; ; skin of thigh; ; ganglionic eminence; ; islet of Langerhans; ; nipple; ; granulocyte; ; ventricular zone;
	Top expressed in
	zygote; ; proximal tubule; ; right kidney; ; secondary oocyte; ; primary oocyte; ; human kidney; ; interventricular septum; ; yolk sac; ; muscle of thigh; ; Rostral migratory stream;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; antioxidant activity; protein binding; prenyltransferase activity; transferase activity, transferring alkyl or aryl (other than methyl) groups;
Cellular component	cytoplasm; integral component of membrane; integral component of Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; membrane; mitochondrial membranes; Golgi membrane; endoplasmic reticulum; mitochondrion; nucleus;
Biological process	menaquinone biosynthetic process; ubiquinone biosynthetic process; vitamin K biosynthetic process; vitamin K metabolic process; cellular oxidant detoxification; ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate;
	Sources:Amigo / QuickGO
Orthologs
	29914
	71707
	ENSG00000120942
	ENSMUSG00000047719
	Q9Y5Z9
	Q9DC60
	NM_013319; NM_001330349; NM_001330350
	NM_027873
	NP_001317278; NP_001317279; NP_037451
	NP_082149
	Wikidata
View/Edit Human	View/Edit Mouse

UbiA prenyltransferase domain-containing protein 1 (UBIAD1) also known as transitional epithelial response protein 1 (TERE1) is a protein that in humans is encoded by the UBIAD1 gene.

The enzyme is named for its canonical role in ubiquinone production, catalyzing reaction EC 2.5.1.39; it thus has a role in oxidative stress pathways. Recent evidence suggests that ubiad1 has enzymatic activity in the vitamin K pathway, hence a role in blood vessel development.