Ubiquilin 4

UBQLN4
Identifiers
Aliases	UBQLN4, A1U, A1Up, C1orf6, CIP75, UBIN, Ubiquilin 4
External IDs	OMIM: 605440; MGI: 2150152; HomoloGene: 41346; GeneCards: UBQLN4; OMA:UBQLN4 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	156,053,798 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	88,477,032 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; gastrocnemius muscle; ; right frontal lobe; ; cingulate gyrus; ; anterior cingulate cortex; ; caudate nucleus; ; putamen; ; prefrontal cortex; ; tibialis anterior muscle;
	Top expressed in
	ventricular zone; ; muscle of thigh; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; epiblast; ; skeletal muscle tissue; ; yolk sac; ; triceps brachii muscle; ; lip;
	More reference expression data
	n/a
Gene ontology
Molecular function	polyubiquitin modification-dependent protein binding; protein binding; identical protein binding;
Cellular component	cytoplasm; perinuclear region of cytoplasm; autophagosome; nuclear proteasome complex; cytosolic proteasome complex; cytosol; endoplasmic reticulum membrane; cytoplasmic vesicle; endoplasmic reticulum; nucleus; chromosome; site of DNA damage;
Biological process	autophagy; negative regulation of autophagosome maturation; regulation of proteasomal ubiquitin-dependent protein catabolic process; ubiquitin-dependent protein catabolic process; DNA repair; cellular response to DNA damage stimulus; negative regulation of double-strand break repair via homologous recombination;
	Sources:Amigo / QuickGO
Orthologs
	56893
	94232
	ENSG00000160803
	ENSMUSG00000008604
	Q9NRR5
	Q99NB8
	NM_001304342; NM_020131
	NM_033526
	NP_001291271; NP_064516
	NP_277068
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquilin 4 is a protein in humans that is encoded by the UBQLN4 gene. Ubiquilin 4 regulates proteasomal protein degradation.