UBTF

UBTF
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1K99, 1L8Y, 1L8Z, 2HDZ
Identifiers
Aliases	UBTF, NOR-90, UBF, UBF-1, UBF1, UBF2, upstream binding transcription factor, RNA polymerase I, CONDBA, upstream binding transcription factor
External IDs	OMIM: 600673; MGI: 98512; HomoloGene: 7970; GeneCards: UBTF; OMA:UBTF - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	44,221,626 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	102,210,568 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; ganglionic eminence; ; granulocyte; ; right lobe of thyroid gland; ; ventricular zone; ; right coronary artery; ; right hemisphere of cerebellum; ; left lobe of thyroid gland; ; ectocervix; ; body of uterus;
	Top expressed in
	ventricular zone; ; neural layer of retina; ; genital tubercle; ; tail of embryo; ; lip; ; dentate gyrus of hippocampal formation granule cell; ; granulocyte; ; superior frontal gyrus; ; tibiofemoral joint; ; thymus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; RNA polymerase I core promoter sequence-specific DNA binding; RNA polymerase I cis-regulatory region sequence-specific DNA binding; protein binding; chromatin binding; RNA binding; scaffold protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleolus; nucleus; nucleoplasm; fibrillar center;
Biological process	transcription initiation from RNA polymerase I promoter; transcription by RNA polymerase I; termination of RNA polymerase I transcription; positive regulation of transcription by RNA polymerase I; transcription elongation from RNA polymerase I promoter; regulation of glucose mediated signaling pathway; regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase I; RNA polymerase I preinitiation complex assembly; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7343
	21429
	ENSG00000108312
	ENSMUSG00000020923
	P17480
	P25976
	NM_001076683; NM_001076684; NM_014233
NM_001044383; NM_011551; NM_001302954; NM_001302955; NM_001362544;
	NM_001362545; NM_001362547; NM_001362548; NM_001362549; NM_001362550; NM_001362551; NM_001362552
	NP_001070151; NP_001070152; NP_055048
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Upstream binding transcription factor (UBTF), or upstream binding factor (UBF), is a protein that in humans is encoded by the UBTF gene.