UFM1

UFM1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WXS, 5HKH
Identifiers
Aliases	UFM1, BM-002, C13orf20, ubiquitin-fold modifier 1, ubiquitin fold modifier 1, HLD14
External IDs	OMIM: 610553; MGI: 1915140; HomoloGene: 9594; GeneCards: UFM1; OMA:UFM1 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	38,363,619 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	53,771,251 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; Epithelium of choroid plexus; ; caput epididymis; ; seminal vesicula; ; internal globus pallidus; ; tail of epididymis; ; body of pancreas; ; Achilles tendon; ; endometrium; ; sperm;
	Top expressed in
	right kidney; ; ventricular zone; ; embryo; ; embryo; ; yolk sac; ; lip; ; morula; ; muscle of thigh; ; superior frontal gyrus; ; cardiac muscle tissue of left ventricle;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; nucleus; endoplasmic reticulum;
Biological process	regulation of intracellular estrogen receptor signaling pathway; protein K69-linked ufmylation; response to endoplasmic reticulum stress; protein ufmylation; negative regulation of apoptotic process; brain development;
	Sources:Amigo / QuickGO
Orthologs
	51569
	67890
	ENSG00000120686
	ENSMUSG00000027746
	P61960
	P61961
	NM_001286703; NM_001286704; NM_001286705; NM_001286706; NM_016617
	NM_026435
	NP_001273632; NP_001273633; NP_001273634; NP_001273635; NP_057701
	NP_080711
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin-fold modifier 1, also known as UFM1, is a protein which in humans is encoded by the UFM1 gene.

UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 and E2-like conjugating enzyme UFC1. This process is often referred to as UFMylation.