UGT2B10

UGT2B10
Identifiers
Aliases	UGT2B10, UDPGT2B10, UDP glucuronosyltransferase family 2 member B10
External IDs	OMIM: 600070; MGI: 2140962; HomoloGene: 117389; GeneCards: UGT2B10; OMA:UGT2B10 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	68,832,023 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	87,054,796 bp
RNA expression pattern
	Top expressed in
	liver; ; right lobe of liver; ; testicle; ; gallbladder; ; rectum; ; mucosa of transverse colon; ; islet of Langerhans; ; kidney; ; renal cortex; ; left testis;
	Top expressed in
	left lobe of liver; ; pyloric antrum; ; mucous cell of stomach; ; left colon; ; jejunum; ; duodenum; ; migratory enteric neural crest cell; ; epithelium of stomach; ; ileum; ; gallbladder;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	glycosyltransferase activity; transferase activity; hexosyltransferase activity; glucuronosyltransferase activity; UDP-glycosyltransferase activity;
Cellular component	integral component of membrane; organelle membrane; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; endoplasmic reticulum; membrane;
Biological process	metabolism; lipid metabolism;
	Sources:Amigo / QuickGO
Orthologs
	7365
	100727
	ENSG00000275190; ENSG00000109181
	ENSMUSG00000029260
	P36537
	n/a
	NM_001290091; NM_001075; NM_001144767
	NM_153598
	NP_001066; NP_001138239; NP_001277020
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

UDP-glucuronosyltransferase 2B10 is an enzyme that in humans is encoded by the UGT2B10 gene. It is responsible for glucuronidation of nicotine and cotinine. Due to common hypomorphic alleles of UGT2B10, glucuronidation contributes relatively little to nicotine metabolism in most people.