UGT2B15

UGT2B15
Identifiers
Aliases	UGT2B15, HLUG4, UDPGT 2B8, UDPGT2B15, UDPGTH3, UGT2B8, UDP glucuronosyltransferase family 2 member B15
External IDs	OMIM: 600069; MGI: 1919023; HomoloGene: 133957; GeneCards: UGT2B15; OMA:UGT2B15 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	68,670,652 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	87,074,389 bp
RNA expression pattern
	Top expressed in
	gallbladder; ; liver; ; right lobe of liver; ; gonad; ; islet of Langerhans; ; duodenum; ; mucosa of transverse colon; ; body of pancreas; ; body of stomach; ; rectum;
	Top expressed in
	left lobe of liver; ; embryo; ; lumbar subsegment of spinal cord; ; right ventricle; ; tibiofemoral joint; ; sexually immature organism; ; medial head of gastrocnemius muscle; ; lumbar spinal ganglion; ; stria vascularis; ; carotid body;
	More reference expression data
	n/a
Gene ontology
Molecular function	hexosyltransferase activity; glucuronosyltransferase activity; glycosyltransferase activity; transferase activity; retinoic acid binding; UDP-glycosyltransferase activity;
Cellular component	endoplasmic reticulum membrane; membrane; intracellular membrane-bounded organelle; integral component of membrane; organelle membrane; endoplasmic reticulum;
Biological process	steroid metabolic process; cellular glucuronidation; metabolism; xenobiotic metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	7366
	71773
	ENSG00000277132; ENSG00000196620
	ENSMUSG00000035836
	P54855
	Q8R084
	NM_001076
	NM_152811
	NP_001067
	NP_690024
	Wikidata
View/Edit Human	View/Edit Mouse

UDP-glucuronosyltransferase 2B15 is an enzyme that in humans is encoded by the UGT2B15 gene.

The UGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B8 demonstrates reactivity with estriol. See UGT2B4 (MIM 600067).[supplied by OMIM]