UGT2B17

UGT2B17
Identifiers
Aliases	UGT2B17, BMND12, UDPGT2B17, UDP glucuronosyltransferase family 2 member B17
External IDs	OMIM: 601903; MGI: 1919023; HomoloGene: 68144; GeneCards: UGT2B17; OMA:UGT2B17 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	68,576,413 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	87,074,389 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; mucosa of ileum; ; mucosa of sigmoid colon; ; duodenum; ; appendix; ; epithelium of colon; ; jejunal mucosa; ; rectum; ; right lobe of liver; ; pancreatic epithelial cell;
	Top expressed in
	left lobe of liver; ; embryo; ; lumbar subsegment of spinal cord; ; right ventricle; ; tibiofemoral joint; ; sexually immature organism; ; medial head of gastrocnemius muscle; ; lumbar spinal ganglion; ; stria vascularis; ; carotid body;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	glycosyltransferase activity; transferase activity; glucuronosyltransferase activity; retinoic acid binding; hexosyltransferase activity; UDP-glycosyltransferase activity;
Cellular component	integral component of membrane; organelle membrane; endoplasmic reticulum membrane; membrane; intracellular membrane-bounded organelle; endoplasmic reticulum;
Biological process	steroid metabolic process; metabolism; cellular glucuronidation;
	Sources:Amigo / QuickGO
Orthologs
	7367
	71773
	ENSG00000197888
	ENSMUSG00000035836
	O75795
	Q8R084
	NM_001077
	NM_152811
	NP_001068
	NP_690024
	Wikidata
View/Edit Human	View/Edit Mouse

UDP-glucuronosyltransferase 2B17 is an enzyme that in humans is encoded by the UGT2B17 gene.

UGT2B17 belongs to the family of UDP-glucuronosyltransferases (UGTs; EC 2.4.1.17), enzymes that catalyze the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a variety of substrates, including steroid hormones.[supplied by OMIM] It also metabolizes 3-hydroxycotinine, which is minor nicotine metabolite