UGT8

UGT8
Identifiers
Aliases	UGT8, CGT, UGT4, UDP glycosyltransferase 8, GalCer Synthase, Ceramide Galactosyltransferase
External IDs	OMIM: 601291; MGI: 109522; HomoloGene: 20715; GeneCards: UGT8; OMA:UGT8 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	114,678,225 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	125,732,268 bp
RNA expression pattern
	Top expressed in
	inferior ganglion of vagus nerve; ; corpus callosum; ; subthalamic nucleus; ; superior vestibular nucleus; ; C1 segment; ; Pons; ; external globus pallidus; ; pars reticulata; ; ventral tegmental area; ; pars compacta;
	Top expressed in
	deep cerebellar nuclei; ; pontine nuclei; ; ventral tegmental area; ; lateral geniculate nucleus; ; globus pallidus; ; dorsal tegmental nucleus; ; substantia nigra; ; lateral hypothalamus; ; medial geniculate nucleus; ; medial vestibular nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	hexosyltransferase activity; glycosyltransferase activity; glucuronosyltransferase activity; transferase activity; N-acylsphingosine galactosyltransferase activity; UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity; UDP-glycosyltransferase activity;
Cellular component	integral component of membrane; membrane; intracellular membrane-bounded organelle; plasma membrane;
Biological process	lipid metabolism; neuron projection morphogenesis; galactosylceramide biosynthetic process; glycosphingolipid metabolic process; peripheral nervous system development; central nervous system development; paranodal junction assembly; metabolism; protein localization to paranode region of axon; cytoskeleton organization; sphingolipid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	7368
	22239
	ENSG00000174607
	ENSMUSG00000032854
	Q16880
	Q64676
	NM_001128174; NM_003360; NM_001322112; NM_001322113; NM_001322114
	NM_011674
	NP_001121646; NP_001309041; NP_001309042; NP_001309043; NP_003351
	NP_035804
	Wikidata
View/Edit Human	View/Edit Mouse

2-hydroxyacylsphingosine 1-beta-galactosyltransferase is an enzyme that in humans is encoded by the UGT8 gene.