UIMC1

UIMC1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2MKF, 2MKG, 2RR9, 2N9E
Identifiers
Aliases	UIMC1, RAP80, X2HRIP110, ubiquitin interaction motif containing 1
External IDs	OMIM: 609433; MGI: 103185; HomoloGene: 9455; GeneCards: UIMC1; OMA:UIMC1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	177,022,633 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	55,248,113 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; sural nerve; ; Achilles tendon; ; monocyte; ; left ovary; ; granulocyte; ; right ovary; ; epithelium of colon; ; body of uterus;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; epiblast; ; tunica media of zone of aorta; ; Paneth cell; ; gastrula; ; mesenteric lymph nodes; ; body of femur; ; spleen; ; hair follicle; ; bone marrow;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	histone binding; K63-linked polyubiquitin modification-dependent protein binding; protein binding;
Cellular component	BRCA1-A complex; nucleus; nucleoplasm; nuclear body;
Biological process	response to ionizing radiation; positive regulation of DNA repair; histone H2A K63-linked deubiquitination; negative regulation of transcription, DNA-templated; double-strand break repair via nonhomologous end joining; regulation of transcription, DNA-templated; transcription, DNA-templated; cellular response to DNA damage stimulus; double-strand break repair; DNA repair; protein deubiquitination; mitotic G2 DNA damage checkpoint signaling; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	51720
	20184
	ENSG00000087206
	ENSMUSG00000025878
	Q96RL1
	Q5U5Q9
	NM_001199297; NM_001199298; NM_016290; NM_001317961
	NM_001293660; NM_011307; NM_001359757; NM_001359758
	NP_001186226; NP_001186227; NP_001304890; NP_057374
	NP_001280589; NP_035437; NP_001346686; NP_001346687
	Wikidata
View/Edit Human	View/Edit Mouse

BRCA1-A complex subunit RAP80 is a protein that in humans is encoded by the UIMC1 gene.