UMkhuze Game Reserve
| uMkhuze Game Reserve | |
|---|---|
| Nyala ewes in the reserve | |
| Location | KwaZulu-Natal | 
| Nearest city | Richards Bay | 
| Coordinates | 27°39′0″S 32°15′0″E / 27.65000°S 32.25000°E | 
| Area | 40,000 ha (150 sq mi) | 
| Established | 1912 | 
| Governing body | Ezemvelo KZN Wildlife | 
uMkhuze Game Reserve (also spelt Mkhuze or Mkuze) is a 40,000-hectare (400 km2; 150 sq mi) game reserve in northern Zululand, KwaZulu-Natal, South Africa. It was proclaimed a protected area on 15 February 1912.