UNC5A

UNC5A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4V2A
Identifiers
Aliases	UNC5A, UNC5H1, unc-5 netrin receptor A
External IDs	OMIM: 607869; MGI: 894682; HomoloGene: 41474; GeneCards: UNC5A; OMA:UNC5A - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	176,880,898 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	55,153,831 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; middle temporal gyrus; ; Brodmann area 23; ; primary visual cortex; ; right hemisphere of cerebellum; ; right frontal lobe; ; prefrontal cortex; ; superior frontal gyrus; ; Brodmann area 9; ; postcentral gyrus;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; secondary oocyte; ; superior frontal gyrus; ; lumbar subsegment of spinal cord; ; hippocampus proper; ; humerus; ; transitional epithelium of urinary bladder; ; primary oocyte; ; neural layer of retina;
	More reference expression data
	n/a
Gene ontology
Molecular function	netrin receptor activity;
Cellular component	intrinsic component of plasma membrane; integral component of membrane; neuronal cell body membrane; membrane raft; plasma membrane; cell projection; neuron projection membrane; membrane;
Biological process	multicellular organism development; neuron projection development; signal transduction; anterior/posterior axon guidance; axon guidance; apoptotic process; netrin-activated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	90249
	107448
	ENSG00000113763
	ENSMUSG00000025876
	Q6ZN44
	Q8K1S4
	NM_133369
	NM_153131; NM_001311128
	NP_588610
	NP_001298057; NP_694771
	Wikidata
View/Edit Human	View/Edit Mouse

Netrin receptor UNC5A is a protein that in humans is encoded by the UNC5A gene.

UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).[supplied by OMIM]