UPF2

UPF2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1UW4, 2WJV, 4CEK, 4CEM
Identifiers
Aliases	UPF2, HRENT2, smg-3, UPF2 regulator of nonsense transcripts homolog (yeast), regulator of nonsense mediated mRNA decay, UPF2 regulator of nonsense mediated mRNA decay
External IDs	OMIM: 605529; MGI: 2449307; HomoloGene: 6101; GeneCards: UPF2; OMA:UPF2 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	12,043,170 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	6,061,514 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; Achilles tendon; ; tendon of biceps brachii; ; internal globus pallidus; ; sperm; ; testicle; ; biceps brachii; ; ventricular zone; ; Skeletal muscle tissue of biceps brachii; ; Skeletal muscle tissue of rectus abdominis;
	Top expressed in
	saccule; ; utricle; ; urothelium; ; motor neuron; ; ciliary body; ; primary oocyte; ; ectoderm; ; vestibular sensory epithelium; ; otic vesicle; ; transitional epithelium of urinary bladder;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; telomeric DNA binding; RNA binding;
Cellular component	cytoplasm; perinuclear region of cytoplasm; exon-exon junction complex; nucleus; cytosol; polysome; cytoplasmic ribonucleoprotein granule;
Biological process	liver development; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; mRNA export from nucleus; animal organ regeneration;
	Sources:Amigo / QuickGO
Orthologs
	26019
	326622
	ENSG00000151461
	ENSMUSG00000043241
	Q9HAU5
	A2AT37
	NM_015542; NM_080599
	NM_001081132
	NP_056357; NP_542166
	NP_001074601
	Wikidata
View/Edit Human	View/Edit Mouse

Regulator of nonsense transcripts 2 is a protein that in humans is encoded by the UPF2 gene.