Uroporphyrinogen III decarboxylase

UROD
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1JPH, 1JPI, 1JPK, 1R3Q, 1R3R, 1R3S, 1R3T, 1R3V, 1R3W, 1R3Y, 1URO, 2Q6Z, 2Q71, 3GVQ, 3GVR, 3GVV, 3GVW, 3GW0, 3GW3
Identifiers
Aliases	UROD, PCT, UPD, uroporphyrinogen decarboxylase
External IDs	OMIM: 613521; MGI: 98916; HomoloGene: 320; GeneCards: UROD; OMA:UROD - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	45,015,575 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	116,851,610 bp
RNA expression pattern
	Top expressed in
	trabecular bone; ; parotid gland; ; right adrenal gland; ; right adrenal cortex; ; parietal pleura; ; left adrenal cortex; ; endothelial cell; ; middle temporal gyrus; ; Brodmann area 23; ; bone marrow;
	Top expressed in
	fetal liver hematopoietic progenitor cell; ; internal carotid artery; ; endocardial cushion; ; human fetus; ; external carotid artery; ; facial motor nucleus; ; atrioventricular valve; ; Epithelium of choroid plexus; ; medullary collecting duct; ; renal corpuscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; lyase activity; uroporphyrinogen decarboxylase activity; carboxy-lyase activity;
Cellular component	nucleoplasm; cytoplasm; cytosol;
Biological process	protoporphyrinogen IX biosynthetic process; porphyrin-containing compound biosynthetic process; heme biosynthetic process; heme metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	7389
	22275
	ENSG00000126088
	ENSMUSG00000028684
	P06132
	P70697
	NM_000374
	NM_009478
	NP_000365
	NP_033504
	Wikidata
View/Edit Human	View/Edit Mouse

Uroporphyrinogen III decarboxylase (uroporphyrinogen decarboxylase, or UROD) is an enzyme (EC 4.1.1.37) that in humans is encoded by the UROD gene.