USP13

USP13
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2L80, 2LBC
Identifiers
Aliases	USP13, ISOT3, IsoT-3, ubiquitin specific peptidase 13 (isopeptidase T-3), ubiquitin specific peptidase 13
External IDs	OMIM: 603591; MGI: 1919857; HomoloGene: 68372; GeneCards: USP13; OMA:USP13 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	179,804,366 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	32,992,220 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of biceps brachii; ; glutes; ; thoracic diaphragm; ; deltoid muscle; ; vastus lateralis muscle; ; tibialis anterior muscle; ; triceps brachii muscle; ; Skeletal muscle tissue of rectus abdominis; ; right ventricle; ; myocardium of left ventricle;
	Top expressed in
	interventricular septum; ; muscle of thigh; ; triceps brachii muscle; ; temporal muscle; ; sternocleidomastoid muscle; ; digastric muscle; ; soleus muscle; ; myocardium of ventricle; ; gastrocnemius muscle; ; skeletal muscle tissue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	cysteine-type peptidase activity; chaperone binding; zinc ion binding; BAT3 complex binding; metal ion binding; ubiquitin-like protein-specific protease activity; proteasome binding; peptidase activity; ubiquitin binding; protein binding; ubiquitin-like protein ligase binding; hydrolase activity; ubiquitin protein ligase binding; thiol-dependent deubiquitinase; cysteine-type endopeptidase activity;
Cellular component	nucleoplasm; cytosol;
Biological process	regulation of transcription, DNA-templated; ubiquitin-dependent protein catabolic process; positive regulation of ERAD pathway; proteolysis; autophagy; regulation of autophagy; protein K63-linked deubiquitination; maintenance of unfolded protein involved in ERAD pathway; cell population proliferation; melanocyte differentiation; protein deubiquitination; protein K29-linked deubiquitination; protein K6-linked deubiquitination; protein stabilization;
	Sources:Amigo / QuickGO
Orthologs
	8975
	72607
	ENSG00000058056
	ENSMUSG00000056900
	Q92995
	Q5BKP2
	NM_003940
	NM_001013024
	NP_003931
	NP_001013042
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin carboxyl-terminal hydrolase 13 is an enzyme that in humans is encoded by the USP13 gene.