USP33

USP33
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2UZG
Identifiers
Aliases	USP33, VDU1, ubiquitin specific peptidase 33
External IDs	OMIM: 615146; MGI: 2159711; HomoloGene: 8996; GeneCards: USP33; OMA:USP33 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	77,759,852 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	152,099,254 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; Brodmann area 23; ; retinal pigment epithelium; ; Pons; ; lateral nuclear group of thalamus; ; mucosa of paranasal sinus; ; parietal pleura; ; primary visual cortex; ; endothelial cell; ; middle temporal gyrus;
	Top expressed in
	neural layer of retina; ; ventromedial nucleus; ; lobe of cerebellum; ; ventral tegmental area; ; mammillary body; ; dorsomedial hypothalamic nucleus; ; pontine nuclei; ; habenula; ; lateral hypothalamus; ; dorsal tegmental nucleus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	cysteine-type peptidase activity; zinc ion binding; metal ion binding; peptidase activity; ubiquitin binding; protein binding; thiol-dependent deubiquitinase; cysteine-type endopeptidase activity; hydrolase activity; G protein-coupled receptor binding;
Cellular component	cytoplasm; cell body; centrosome; Golgi apparatus; VCB complex; focal adhesion; nucleoplasm; microtubule organizing center; autophagosome; perinuclear region of cytoplasm; cytoskeleton; cytosol;
Biological process	endocytosis; protein K48-linked deubiquitination; ubiquitin-dependent protein catabolic process; regulation of G protein-coupled receptor signaling pathway; centrosome duplication; cellular response to starvation; protein stabilization; negative regulation of protein binding; proteolysis; axon guidance; regulation of autophagy; protein K63-linked deubiquitination; positive regulation of protein binding; cell migration; protein deubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	23032
	170822
	ENSG00000077254
	ENSMUSG00000025437
	Q8TEY7
	Q8R5K2
	NM_015017; NM_201624; NM_201626
	NM_001076676; NM_001252486; NM_133247; NM_001355666
NP_055832; NP_963918; NP_963920; NP_001364359; NP_001364360;
	NP_001364361; NP_001364362; NP_001364363; NP_001364364; NP_001364365; NP_001364366; NP_001364367; NP_001364368
	NP_001070144; NP_001239415; NP_573510; NP_001342595
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin carboxyl-terminal hydrolase 33 is an enzyme that in humans is encoded by the USP33 gene.