USP47

USP47
Identifiers
Aliases	USP47, TRFP, ubiquitin specific peptidase 47
External IDs	OMIM: 614460; MGI: 1922246; HomoloGene: 9929; GeneCards: USP47; OMA:USP47 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	11,959,323 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	111,710,868 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; internal globus pallidus; ; endothelial cell; ; glutes; ; secondary oocyte; ; seminal vesicula; ; vena cava; ; corpus callosum; ; biceps brachii; ; periodontal fiber;
	Top expressed in
	ciliary body; ; vastus lateralis muscle; ; triceps brachii muscle; ; spermatid; ; gastrocnemius muscle; ; tibialis anterior muscle; ; medial head of gastrocnemius muscle; ; ankle; ; spermatocyte; ; muscle of thigh;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	WD40-repeat domain binding; peptidase activity; hydrolase activity; cysteine-type peptidase activity; thiol-dependent deubiquitinase; protein binding; deubiquitinase activity; cysteine-type endopeptidase activity;
Cellular component	cytoplasm; SCF ubiquitin ligase complex; nucleoplasm; cytosol;
Biological process	ubiquitin-dependent protein catabolic process; proteolysis; negative regulation of apoptotic process; cellular response to UV; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; DNA repair; positive regulation of cell growth; monoubiquitinated protein deubiquitination; base-excision repair; negative regulation of G2/M transition of mitotic cell cycle; negative regulation of transcription, DNA-templated; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; cellular response to DNA damage stimulus; protein deubiquitination; positive regulation of canonical Wnt signaling pathway; regulation of protein stability;
	Sources:Amigo / QuickGO
Orthologs
	55031
	74996
	ENSG00000170242
	ENSMUSG00000059263
	Q96K76
	Q8BY87
	NM_001282659; NM_017944; NM_001330208
	NM_133758; NM_177249; NM_001357952
NP_001269588; NP_001317137; NP_060414; NP_001359020; NP_001359021;
	NP_001359022; NP_001359023; NP_001359024; NP_001359025; NP_001359026; NP_001359027; NP_001359028; NP_001359029; NP_001359030; NP_001359031; NP_001359032
	NP_598519; NP_796223; NP_001344881; NP_001390423
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin carboxyl-terminal hydrolase 47 is an enzyme that in humans is encoded by the USP47 gene.