Utrophin

UTRN
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	1BHD, 1QAG,%%s1BHD, 1QAG
Identifiers
Aliases	UTRN, DMDL, DRP, DRP1, utrophin
External IDs	OMIM: 128240; MGI: 104631; HomoloGene: 21398; GeneCards: UTRN; OMA:UTRN - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	144,853,034 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	12,745,109 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; sural nerve; ; tendon of biceps brachii; ; trigeminal ganglion; ; epithelium of colon; ; monocyte; ; visceral pleura; ; pericardium; ; parietal pleura; ; epithelium of nasopharynx;
	Top expressed in
	iris; ; ciliary body; ; Paneth cell; ; ascending aorta; ; aortic valve; ; vestibular membrane of cochlear duct; ; retinal pigment epithelium; ; fossa; ; right lung; ; right lung lobe;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	vinculin binding; zinc ion binding; metal ion binding; integrin binding; actin filament binding; protein binding; actin binding; protein kinase binding;
Cellular component	cytoplasm; postsynaptic membrane; contractile ring; membrane; filopodium; growth cone; neuromuscular junction; plasma membrane; synapse; dystrophin-associated glycoprotein complex; nucleoplasm; cell junction; cortical actin cytoskeleton; sarcolemma; extracellular exosome; cytoskeleton; filopodium membrane; protein-containing complex;
Biological process	muscle contraction; positive regulation of cell-matrix adhesion; muscle organ development; neuromuscular junction development; regulation of sodium ion transmembrane transporter activity; response to denervation involved in regulation of muscle adaptation;
	Sources:Amigo / QuickGO
Orthologs
	7402
	22288
	ENSG00000152818
	ENSMUSG00000019820
	P46939; Q5T097
	n/a
	NM_007124; NM_001375323
	NM_011682
	NP_009055; NP_001362252
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Utrophin is a protein that in humans is encoded by the UTRN gene. The name is a short form for ubiquitous dystrophin. The 900 kb gene for utrophin is found on the long arm of human chromosome 6.