VAMP2

VAMP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3FIE, 3FII, 3RK2, 3RK3, 3RL0
Identifiers
Aliases	VAMP2, SYB2, VAMP-2, vesicle associated membrane protein 2, NEDHAHM
External IDs	OMIM: 185881; MGI: 1313277; HomoloGene: 7591; GeneCards: VAMP2; OMA:VAMP2 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	8,163,546 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	68,983,210 bp
RNA expression pattern
	Top expressed in
	Brodmann area 10; ; frontal pole; ; paraflocculus of cerebellum; ; right frontal lobe; ; right hemisphere of cerebellum; ; cingulate gyrus; ; anterior cingulate cortex; ; Amygdala; ; nucleus accumbens; ; anterior pituitary;
	Top expressed in
	perirhinal cortex; ; entorhinal cortex; ; superior frontal gyrus; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; neural layer of retina; ; CA3 field; ; cerebellar cortex; ; prefrontal cortex; ; subiculum;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	SNAP receptor activity; protein self-association; protein binding; syntaxin-1 binding; SNARE binding; calmodulin binding; syntaxin binding; phospholipid binding; calcium-dependent protein binding;
Cellular component	integral component of membrane; cytosol; clathrin-sculpted monoamine transport vesicle membrane; membrane; secretory granule membrane; plasma membrane; clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane; synapse; integral component of plasma membrane; synaptic vesicle membrane; zymogen granule membrane; cell junction; neuron projection; cytoplasmic vesicle; clathrin-coated vesicle; clathrin-sculpted glutamate transport vesicle membrane; secretory granule; intracellular membrane-bounded organelle; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex; synaptobrevin 2-SNAP-25-syntaxin-1a complex; SNARE complex; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex; voltage-gated potassium channel complex; trans-Golgi network; synaptic vesicle; vesicle; perinuclear region of cytoplasm; neuron projection terminus; clathrin-coated vesicle membrane;
Biological process	natural killer cell degranulation; mucus secretion; regulation of histamine secretion by mast cell; neutrophil degranulation; glutamate secretion; vesicle fusion; eosinophil degranulation; vesicle-mediated transport; exocytosis; response to glucose; membrane fusion; regulation of delayed rectifier potassium channel activity; calcium-ion regulated exocytosis; regulation of exocytosis; positive regulation of intracellular protein transport; protein transport; Golgi to plasma membrane protein transport; synaptic vesicle exocytosis; cellular response to insulin stimulus; long-term potentiation; regulation of vesicle-mediated transport; membrane organization; protein-containing complex assembly; post-Golgi vesicle-mediated transport; neurotransmitter secretion;
	Sources:Amigo / QuickGO
Orthologs
	6844
	22318
	ENSG00000220205
	ENSMUSG00000020894
	P63027
	P63044
	NM_014232; NM_001330125
	NM_009497
	NP_001317054; NP_055047
	NP_033523
	Wikidata
View/Edit Human	View/Edit Mouse

Vesicle-associated membrane protein 2 (VAMP2) is a protein that in humans is encoded by the VAMP2 gene.