VPS18

VPS18
Identifiers
Aliases	VPS18, PEP3, CORVET/HOPS core subunit, VPS18 core subunit of CORVET and HOPS complexes
External IDs	OMIM: 608551; MGI: 2443626; HomoloGene: 13302; GeneCards: VPS18; OMA:VPS18 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	40,903,975 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	119,128,934 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; tendon of biceps brachii; ; stromal cell of endometrium; ; apex of heart; ; tibialis anterior muscle; ; blood; ; muscle of thigh; ; islet of Langerhans; ; prefrontal cortex; ; white blood cell;
	Top expressed in
	ankle joint; ; neural layer of retina; ; granulocyte; ; yolk sac; ; stroma of bone marrow; ; primary visual cortex; ; superior frontal gyrus; ; right kidney; ; dentate gyrus of hippocampal formation granule cell; ; muscle of thigh;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein-macromolecule adaptor activity; metal ion binding; protein binding; actin binding; syntaxin binding;
Cellular component	HOPS complex; AP-3 adaptor complex; endosome; late endosome; membrane; late endosome membrane; autophagosome; lysosomal membrane; early endosome; actin filament; CORVET complex; lysosome; cytoplasmic vesicle; clathrin-coated vesicle; presynapse; glutamatergic synapse;
Biological process	endosome to lysosome transport; endosome organization; autophagy; protein transport; viral entry into host cell; intracellular protein transport; lysosome organization; vesicle-mediated transport; vesicle docking involved in exocytosis; regulation of SNARE complex assembly; transport; regulation of synaptic vesicle exocytosis; vacuole organization;
	Sources:Amigo / QuickGO
Orthologs
	57617
	228545
	ENSG00000104142
	ENSMUSG00000034216
	Q9P253
	Q8R307
	NM_020857
	NM_172269
	NP_065908; NP_065908.1
	NP_758473
	Wikidata
View/Edit Human	View/Edit Mouse

Vacuolar protein sorting-associated protein 18 homolog is a protein that in humans is encoded by the VPS18 gene.