VPS39

VPS39
Identifiers
Aliases	VPS39, TLP, VAM6, hVam6p, HOPS complex subunit, VPS39 subunit of HOPS complex
External IDs	OMIM: 612188; MGI: 2443189; HomoloGene: 41025; GeneCards: VPS39; OMA:VPS39 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	42,208,307 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	120,183,618 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; granulocyte; ; gastric mucosa; ; skin of leg; ; right lobe of thyroid gland; ; skin of abdomen; ; left lobe of thyroid gland; ; anterior pituitary; ; apex of heart; ; right adrenal cortex;
	Top expressed in
	zygote; ; secondary oocyte; ; primary visual cortex; ; genital tubercle; ; neural layer of retina; ; facial motor nucleus; ; superior frontal gyrus; ; cerebellar cortex; ; motor neuron; ; supraoptic nucleus;
	More reference expression data
	More reference expression data
Orthologs
	23339
	269338
	ENSG00000166887
	ENSMUSG00000027291
	Q96JC1
	Q8R5L3
	NM_001301138; NM_015289
	NM_147153; NM_178851; NM_001363053; NM_001363054
	NP_001288067; NP_056104
	NP_671495; NP_849182; NP_001349982; NP_001349983
	Wikidata
View/Edit Human	View/Edit Mouse

hVamp6/Vps39-like protein is a protein that in humans is encoded by the VPS39 gene.

This gene encodes a protein that may promote clustering and fusion of late endosomes and lysosomes. The protein may also act as an adaptor protein that modulates the transforming growth factor-beta response by coupling the transforming growth factor-beta receptor complex to the Smad pathway.